The commonly used anti-malarial drug is mefloquine. It is effective against all species of malaria, including chloroquine-resistant P. falciparum. Mefloquine is often used as a prophylactic drug for travelers to malaria-endemic areas. However, its use has been limited due to its potential side effects, which include nausea, dizziness, and neuropsychiatric effects such as anxiety, depression, and psychosis. Doxycycline is another Anti-malarial Drugs used for prophylaxis and treatment of malaria. It is effective against P. falciparum and P. vivax, but not against P. malariae or P. ovale. Doxycycline is often used in combination with other drugs, such as quinine, for the treatment of severe malaria. However, its use is limited due to its potential side effects, which include gastrointestinal upset, photosensitivity, and rare but serious side effects such as liver and kidney damage.
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