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Double Marker Test During Pregnancy
A doctor usually prescribes the Double marker test as part of standard prenatal care during the first trimester. It is a predictive test that determines whether or not the growing foetus has any chromosomal abnormalities. Although the test is suggested for all women, women over 35 are especially advised to have it done because conceiving a baby with genetic abnormalities increases with age.

Double Marker Test During Pregnancy

Double Marker Test During Pregnancy: Why is It Done, Cost in India, Results

redcliffelabs.com · by Srujana Mohanty · February 15, 2022

 

A doctor usually prescribes the Double marker test as part of standard prenatal care during the first trimester. It is a predictive test that determines whether or not the growing foetus has any chromosomal abnormalities. Although the test is suggested for all women, women over 35 are especially advised to have it done because conceiving a baby with genetic abnormalities increases with age.

 

Let us look at what a double marker test is and the results.

 

What exactly is a double Marker test?

 

A double marker test is a predictive analysis performed during the first trimester to look for illnesses or congenital problems in the foetus. The levels of two major hormones are checked during this test: the free Beta Human Chorionic Gonadotropin and pregnancy-associated plasma protein-A. The test is usually done in the week 11-14 of pregnancy.

 

When should a woman get a double marker test?

 

The Double marker test is a routine diagnostic assessment for most pregnant women. However, certain women are at a higher risk of having kids with congenital disabilities, necessitating a double marker test.

 

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Why is it done?

 

A double Marker test is quite successful in predicting the foetus against a variety of illnesses such as

 

Edward syndrome

 

It is caused by the trisomy of 18 (three copies of chromosome 18)which can have a severe influence on normal mental health, including developmental disorders and various verbal problems. These can be detected with a Double Marker test.

 

Down’s syndrome:

 

It is characterised by chromosomal trisomy 21. It is distinguished by several cognitive, behavioural, and medical concerns. The test is also helpful in determining if the baby will have muscle mass loss, excessive skin development at the back of the neck, or a short neck.

 

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Microcephaly detection

 

Test can detect head defects in the foetus, such as microcephaly, in which the head is undeveloped and small. This is seen in infants born with Patau syndrome( trisomy of 13)

 

Micrognathia detection

 

A dual marker test can successfully screen for micrognathia in newborns with atypical jaws and arched spines.

 

What is the cost of the Double Marker test?

 

The cost of the double marker test is affordable because it is a simple pregnancy test that is required for screening. The final Double Marker test cost in India varies depending on the city, laboratories, the availability and quality of the testing, and the diagnostic centre accreditation. On average, the cost might range between INR 1500 and INR 3500.

 

Results of a double Marker test?

 

A double marker test results are generally put into two different categories.

 

Risk Hormone Concentration Inference Low-risk/Screen Negative level of HCG is roughly 25700-288000 mIU/ml
Levels of PAPP – A is 1 MoM (multiples of median) The hormonal concentrations here are closer to normal.
Low probability of baby with a chromosomal abnormality. Moderate to high/ Screen Positive Extreme variance from normal levels Aditional conclusive tests, such as non-invasive prenatal testing or amniocentesis, must be performed.

 

Takeaway

 

A double marker test is a necessary predictive test to identify abnormalities early, although it is not mandatory. Having the test done can give additional information that can help in the progress of your pregnancy and the overall management of your pregnancy.

 

FAQ:

 

What is the difference between an NT scan and a double marker test?

 

An NT scan is another diagnostic test performed during the first trimester of pregnancy. It is a type of ultrasound in which the foetus is examined for abnormalities such as Down syndrome. Nt scan is generally less effieicent as compared to the double marker test.

 

It generates images of the foetus in real-time. A dual or double marker test, on the other hand, is a blood test that looks for congenital abnormalities in the foetus in the mother’s blood.

 

Usually, both these tests are performed together in the first trimester to get a clear insight.

 

 

I will get the double marker test report in how many days?

 

Various testing laboratories provide test results in different time frames. You may receive your double marker test report images within 24-48 hours after your test if you book a test with a Redcliffe. Redcliffe offers free home sample collection faculty with quick report delivery.

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