A class of genetic blood illnesses known as Hemoglobinopathy affect the hemoglobin molecule. Anemia and other severe health issues can be brought on by these illnesses. Hemoglobinopathies come in a wide variety of forms, and they are categorized based on the kind of mutation that occurs in the hemoglobin gene. Red blood cells are specifically affected by hemoglobinopathies, a type of blood condition. The aberrant structure of the globin chains in the haemoglobin molecule is the result of a genetic abnormality.
The most common Hemoglobinopathy diseases include sickle cell anemia, thalassemia, haemoglobin C disease, and haemoglobin S-C disease. Regular RBC counting, genetic testing, and haemoglobin measurements using high performance liquid chromatography, haemoglobin isoelectric focusing (Hb IEF), haemoglobin electrophoresis (Hb ELP), and haemoglobin solubility testing can all identify these disorders, which are typically inherited from single-gene disorders.
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