Ubiquitin Enzymes that aid in transcriptional instruction, protein transport, including endocytosis and lysosomal leveling during signaling

The initial stage in the ubiquitination reaction, which among other things can target a protein for degradation via a proteasome, is catalysed by Ubiquitin Enzymes, also referred to as E1 enzymes. One important mechanism for controlling protein function in eukaryotic organisms is the covalent connection formed between targeted proteins and ubiquitin or ubiquitin-like proteins. The post-translational modification of several processes, including cell division, immunological responses, and embryonic development, is also regulated by ubiquitin and ubiquitin-like proteins.

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