Dexamethasone is a commonly used veterinary drug in pig farms. It is a widely used adrenocortical hormone drug for the treatment of pig diseases. It has anti-inflammatory, anti-allergic, anti-shock and anti-toxic effects. First aid medication.
It is often used in the treatment of severe inflammation and vaccine stress first aid in pig farms. Because of its obvious antipyretic effect, many pig farms and veterinarians use it as a routine antipyretic in clinical practice, and even use it as a panacea for every illness, causing serious adverse consequences for pig farms. The licensed veterinarian from Zhu Bingtong summarized the precautions when using dexamethasone to remind everyone!
1. Dexamethasone has no inhibitory effect on pathogenic microorganisms
Dexamethasone can only reduce or inhibit inflammation, but not cure the symptoms. When used for infectious swine disease, it must be used in conjunction with sufficient and effective antibiotics, and at the same time, try to use a small dose. After the disease is controlled, the dose should be reduced or stopped. medicine.
2. Pregnant sows should be used with caution or disabled
The use of pregnant sows, especially in the early gestation, may affect fetal development, and even lead to malformed fetuses, mummified fetuses, and stillbirths. It also has the effect of exciting uterine smooth muscle, which can cause uterine contraction and cause abortion in pregnant sows. Heavy use of dexamethasone can result in farrowing within 48 hours of late gestation sows.
3. Cannot be used for vaccination period
Dexamethasone can inhibit the immune response, inhibit protein synthesis and affect the production of antibodies, indirectly affect the production of antibodies, affect the immune titer of vaccines, and cause the level of antibodies to decrease, thereby affecting the immune effect and even causing immune failure. Therefore, after treating allergic reactions to vaccines with dexamethasone, it is recommended to supplement the vaccine again.
4. Sudden discontinuation after long-term high-dose continuous use
High-dose continuous medication should not exceed 1 week to avoid the recurrence of diseased pigs or the symptoms of adrenal insufficiency. The diseased pigs show depression, loss of appetite, fever, vomiting, weakness, hypoglycemia, hypotension, and some pigs will also Shock occurs.
5. Domestic animals with heart disease should be banned
Pigs with heart disease should be banned, and pigs with heart insufficiency and severe heart disease should not be used. In addition, pigs with liver and kidney insufficiency should also be used with caution.
6. The dose should be gradually reduced, and the drug should be discontinued slowly, not abruptly.
During the use of dexamethasone, attention should be paid to reducing the dose and gradually stopping to prevent the occurrence of hypotension, hypoglycemia, shock, etc. due to sudden withdrawal of the drug, which may cause the disease to be repeated or aggravated.
7. Long-term use of dexamethasone should pay attention to calcium supplementation
Long-term use should be properly supplemented with phosphorus and calcium to prevent osteoporosis and metabolic disorders; it is forbidden for newborn piglets, and it is used with caution in postpartum paralysis and aging pigs.
8. It should be disabled in some special cases
Pigs with severe osteochondrosis, osteoporosis, fracture treatment period, wound repair period, early corneal ulcer, poor liver function, and infectious diseases lacking effective antibiotic treatment should be banned.
9. Incompatibility between dexamethasone and drugs
Dexamethasone cannot be used together with many drugs. It should be checked when using it. In fact, no matter what kind of drug it is, you must read the instruction manual carefully before using it, otherwise it will cause ineffectiveness or poisoning.
Such as: dexamethasone and diuretics or amphotericin B can promote potassium excretion, pay attention to potassium supplementation when using. It can accelerate the elimination of salicylate and reduce its curative effect. At the same time, the combination of the two drugs is more likely to cause peptic gastric ulcer.
